Partnering

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With the aim of establishing strategic partnerships with industry leaders, we offer access to our technological expertise through multiple entry points. Let’s connect to identify the approach that best aligns with your specific needs.

Primary and secondary assay development

  • Development of human stem cell-based disease models.
  • Phenotype identification in human disease models.
  • Human cell type-specific imaging-based primary screening assays.
  • Function-focused secondary screening assays (i.e. mitochondria, electrophysiology, calcium imaging, plate reader-based assays).
  • Complex readouts development: Multi-protein phenotypic profiling (immunofluorescence) or multi-organelle phenotypic profiling (Cell Painting).
  • Focused single target readout development.
Assay Development

Screening solution

  • Sterile robotic screening platform suitable for non-standard screens (complex treatment schemes, multiple media changes, long culture durations).
  • Imaging-based screening in complex human cell systems (i.e. neurons, cardiomyocytes, microglia).
  • Small molecule screening using our in-house bioactive or diverse chemical libraries or external libraries.

Target identification

  • siRNA/CRISPR screening for gene or target identification.
  • “Smart screening” solutions focusing on most relevant biological pathways.
  • Structure based target hypothesis building.
DB String Network AutismRiskGenes
PD Heatmap

Data science

  • In-house image and data analysis using customizable workflows adapted to handling large imaging data volumes.
  • Screen data analysis for hit identification using phenotypic profiling or individual features.
  • Imaging-based single cell classification.
  • Integration of omics (RNA-seq, proteomics) with imaging data sets.
  • Knowledge graphs for hypothesis development.

Package solution

  • Development of custom screening solutions.
  • Seamless integration of services: Primary and secondary screening, dose-response testing, functional validation, data analysis and reporting.
  • Complex readouts development: Multi-protein phenotypic profiling (immunofluorescence) or multi-organelle phenotypic profiling (Cell Painting).
  • Service bundling: We offer bundled packages that combine multiple services for a comprehensive solution.
Microglia Overview

Testimonials from our strategic partners

“We strongly believe in Ksilink as a key player for effectively bridging the gap between scientific excellence and the pharma industry.”

Jacques Volckmann

Head of R&D, Sanofi, France

“Ksilink’s capacities to apply patient-derived disease models for high-throughput, high-content screening by using AI-driven deep learning computation is outstanding.”

Wolfram Zimmermann

CSO, Myriamed GmbH, Germany

“We see big value in the ability of Ksilink to translate clinical expertise into treatment for diseases with high unmet medical need .”

Andreas Meyer-Lindenberg

Director and CEO, Central Institute of Mental Health, Germany

“We strongly believe in Ksilink’s potential, allowing the generation of valuable first-in-class therapeutic molecules.”

Bert Klebl

Managing Director, Lead Discovery Center, Germany